Okay here's a strange one.
I put together an AMD setup for my HTPC. It's running WinXP w SP2 (recently found out there was a fix for AMP platforms running WinXp wSP3, but I haven't upgraded yet). Well I had a temporary hard-drive in it a few months ago, and noticed that every once and a while Outlook Express would just open up. Be watching a DVD, and O Express would just open...etc. I also noticed that Zoom Player movie properties would open too.
Well, since then, I upgraded the drive to a newer SATA drive, which meant the system was all re-installed. The OS and all applications were re-installed from scratch. The only thing copied over was Xlobby, and the Mirage skin. Well Outlook Express continued to open randomly. So I un-installed it, as it is not needed on this machine. Well now, Window's calculator now opens randomly. And I'm still getting the issue of Zoom Player's video properties window opening randomly. I also have had Zoom Player automatically adjust the video size on the fly for no reason.
I've done virus checks, and they all come up negative. The system does not access the internet except for dragging DVD artwork from the DVDEmpire.com site (via ANT). Other than that, all other installed software, if downloaded, is done from another computer, so I'm pretty confident that there isn't a trojan or virus. The only thing I can figure what is different between this system and all others is the fact that this system is AMD based, whereas all my other systems are Intel...running various Win OS platforms, but I don't understand why that would cause this random issues.