Ive been wondering same thing. Short answer is: it wont. With open pandora theres two obstacles: u can only launch 1 instance of application (this is not however inherent from pandora, so mayby if we plead to author...) also u cant set it to output specific sound renderer...
Long answer is mayby, if somebody comes up with clever hack...
EDIT: all that applies if u are driving zones with one host... ofcourse its entirely different story if u have host on each zone...
Also i have no luck with CTRL+WIN+PG DN / UP hotkeys (station change)... anybody else has same prob?